**Directions to San Manuel Casino** San Manuel Casino is a Native American casino and resort located in Highland, California. It is owned and operated by the San Manuel Band of Mission Indians. The casino features over 2,500 slot machines, 100 table games, and a 2,000-seat bingo hall. It also has a variety of restaurants, bars, and shops. **How to Get to San Manuel Casino** The San Manuel Casino is located about 45 miles east of Los Angeles. There are a few different ways to get there. * **By car:** The casino is located off Interstate 10, Exit 105. From Los Angeles, take Interstate 10 east to Exit 105. The casino will be on your right. * **By bus:** There are several bus routes that stop at the casino. The Riverside Transit Agency (RTA) Route 60 stops at the casino. The San Bernardino County Transportation Authority (SBCTA) Route 218 also stops…